The most important members of this group of drugs are the β-lactamantibiotics, vancomycin, and daptomycin. They have little or no effect on bacteria that are not growing and dividing. Inhibitors of cell wall synthesis require actively proliferating microorganisms. The cell wall is composed of a polymer called peptidoglycan that consists of glycan units joined to each other by peptide cross-links. Some antimicrobial drugs selectively interfere with synthesis of the bacterial cell wall-a structure that mammalian cells do not possess.
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